Last names starting with "O"
- Class of 1966 Mary O'Brien
- Class of 1965 Linda Oakes
- Class of 1966 Pauline Odom (formerly Sanders)
- Class of 2012 Coty Ogg
- Class of 2001 Roland Oliver
- Class of 1969 Veronica Oliver
- Class of 1960 Jane Ols
- Lola Olson
- Class of 1940 Helen Oneil
- Class of 1986 Antonio Ortiz
- Class of 1984 Vivian Ortiz
- Class of 1947 Walter Dyer Osborn
- Class of 1984 Richard Otero
- Class of 1960 Thomas Overman
- Class of 1965 Mary Overstreet
- Class of 1966 Elizabeth Owen
- Class of 1979 Celeste Owens
- Class of 2019 Josh Owens
- Patsy Owens
- Class of 1986 Pamela Oxendine
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